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doi: 10.1161/CIRCULATIONAHA.113.005081 34 CastanedaAMDutra-RufatoAJuarezMJGrosembacherLGonzalez-TorresHMussoCG

Manufacturing, scale-up, and regulatory hurdles Mass production of replicable, clinical-grade scaffolds seeded with viable adipose-derived cells is difficult

It reduces blood pressure by 14 mmHg versus 6-7 mmHg for semaglutide and tirzepatide, and shows greater lipid improvements

Its safety has been confirmed by a recent study published in Lancet, whereby liraglutide had an efficacy comparable to that of glimepiride, but was associated with fewer cardiovascular events [140]

We really need to be asking ourselves, is it about weight loss or is it about health gain

Consider the figure below